Center for Midlife Science: Improving Health, Enhancing Function

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Project: Michigan Lupus Epidemiology and Surveillance Program Longitudinal Cohort (MiLES)

Initiated in 2013, MiLES is a newly established cohort study which creates and maintains the MiLES Longitudinal Cohort & Biobank, including lupus cases from the southeast Michigan surveillance registry as well as population-based controls.

About the MiLES Study »

Project: Study of Women’s Health Across the Nation (SWAN)

Now in its 30th year, the Study of Women’s Health Across the Nation is a multi-site, multi-ethnic longitudinal, study designed to examine the health — physical, biological, psychological and social changes — of women during the midlife and as they age. The resulting research helps scientists, health care providers and women learn how mid-life experiences affect health and quality of life during the midlife and as they age.

About the SWAN Study »

Project: Michigan Bone Health & Metabolism Study (MBHMS Bone Strength)

The 35-year MBHMS follows the daughters of participants in the historic Tecumseh Community Health Study to evaluate the impact of aging-related processes including menopause and the secular increase in obesity on the development and progression of musculoskeletal disease and declines in physical functioning. This study addresses a significant gap in scientific knowledge that impedes our ability to optimize fracture prevention strategies. If our hypotheses prove correct, baseline external bone size may be used as an additional parameter to identify women most likely to lose bone strength rapidly during the MT and who might benefit from early intervention.

About the MBHMS »