Center for Midlife Science: Improving Health, Enhancing Function

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Project: SWAN Genomic Analyses

SWAN Genomic Analyses performed dense genome-wide genotyping and imputation of genetic variants throughout the genome to the Haplotype Reference Consortium (HRC) reference panel in 1538 SWAN participants. This project enables SWAN to participate in genetic consortia focused on reproductive aging as well as risk factors for health and disease in women with data uploaded to dbGaP. We are also conducting gene-based analyses to assess the association of menopausal traits, including vasomotor symptoms, with genetic loci previously identified to be associated with age at menarche and menopause. (AG 017719)

About the SWAN Genomic Analyses »

Project: Michigan Lupus Epidemiology and Surveillance Program Longitudinal Cohort (MiLES)

Initiated in 2013, MiLES is a newly established cohort study which creates and maintains the MiLES Longitudinal Cohort & Biobank, including lupus cases from the southeast Michigan surveillance registry as well as population-based controls.

About the MiLES Study »

Project: Study of Women’s Health Across the Nation (SWAN)

Now in its 30th year, the Study of Women’s Health Across the Nation is a multi-site, multi-ethnic longitudinal, study designed to examine the health — physical, biological, psychological and social changes — of women during the midlife and as they age. The resulting research helps scientists, health care providers and women learn how mid-life experiences affect health and quality of life during the midlife and as they age.

About the SWAN Study »