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Project: Michigan Lupus Epidemiology and Surveillance Program Longitudinal Cohort (MiLES)

Initiated in 2013, MiLES is a newly established cohort study which creates and maintains the MiLES Longitudinal Cohort & Biobank, including lupus cases from the southeast Michigan surveillance registry as well as population-based controls.

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Project: Michigan Bone Health & Metabolism Study (MBHMS Bone Strength)

The 34-year MBHMS follows the daughters of participants in the historic Tecumseh Community Health Study to evaluate the impact of aging-related processes including menopause and the secular increase in obesity on the development and progression of musculoskeletal disease and declines in physical functioning. This study addresses a significant gap in scientific knowledge that impedes our ability to optimize fracture prevention strategies. If our hypotheses prove correct, baseline external bone size may be used as an additional parameter to identify women most likely to lose bone strength rapidly during the MT and who might benefit from early intervention.

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Project: SWAN Multi-Pollutant Study

The SWAN Multi-Pollutant Study (MPS) was initiated in 2016 to examine health effects of multiple environmental chemical exposures, including perfluoroalkyl and polyfluoroalkyl substances (PFAS), polychlorinated biphenyls (PCBs), organochlorine pesticides, polybrominated diphenyl ethers (PBDEs), metals, phenols, phthalates, and organophosphate pesticide among midlife women. Funded through two R01 grants by the National Institute of Environmental Health and Sciences (NIEHS), the SWAN MPS specifically investigates 1) obesity, type-2 diabetes and related metabolic endpoints; and 2) reproductive health including sex steroid hormones, age at menopause and ovarian aging).

About the SWAN Multi-Pollutant Study »